Experimental models and randomized, controlled human intervention studies have demonstrated that taking a probiotic supplement can restore balance and potentially help combat the signs of aging. A study on 20 healthy, non-obese men aged 18 to 30 found that taking a probiotic supplement daily resulted in significantly less weight and fat mass gain, suggesting that probiotics may be an effective way to prevent weight gain and obesity. Research has also suggested that maintaining a healthy balance of bacteria in the gut can prevent weight gain and control appetite. A study involving 110 women aged 41 to 59 with dry skin found that taking a supplement containing 10 billion CFU per day for 12 weeks resulted in a significant reduction in the appearance and depth of wrinkles, as well as higher skin hydration levels than those of the placebo group.
In addition, a clinical trial revealed that a daily dose of the probiotic bacteria Lactobacillus and Bifidobacterium taken over a period of 12 weeks was sufficient to produce a “moderate but significant improvement” in the score of elderly patients with Alzheimer's on the Mini-Mental Status Examination Scale (MMSE). This test is a standard measure of cognitive decline. The International Scientific Association for Probiotics and Prebiotics defines probiotics as living microorganisms that, when administered in adequate amounts, confer a health benefit to the host. These microorganisms, which consist mainly of bacteria but also include yeasts, are naturally present in fermented foods, can be added to other food products and are available as dietary supplements.
However, not all foods and dietary supplements labeled as probiotics on the market have proven health benefits. For instance, supplementation with Lactobacillus rhamnosus or Lactobacillus paracasei significantly reduced the incidence of atopic dermatitis, while supplementation with Lactobacillus reuteri or Lactobacillus acidophilus did not. Furthermore, the World Gastroenterology Organisation (WGO) recommends that users of probiotic supplements check the labels of probiotic supplements for recommended storage conditions; for example, some require refrigeration, while others can be stored at room temperature. In conclusion, probiotics may be beneficial in some cases to help combat the signs of aging, but more research is needed to determine if they are safe and effective for older adults.
